The use of improved assays that provide better data precision, so that fewer animals are needed per group. B. Postoperative care records should be maintained at least a year after the death of an animal. Describe the fluid-mosaic model of membrane structure. Which of the following statements is/are TRUE regarding preparation of a mouse for surgery? D. If an animal undergoes non-survival surgery, the fur around the surgical site should be clipped and clean instruments should be used. The organization and regulatory agencies only In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). Complete the following nuclear equations. It provides a mechanism for peer evaluation of animal care and use programs B. The three Rs of Russell and Burch stand for what? Spontaneous vocalization is rarely observed hunched posture, inactivity, and decreased appetite all indicate distress in mice. Which of the following represents good practice in oral gavage of mice? A protocol submitted to the IACUC should demonstrate a clear hypothesis driven thought process and a thorough understanding of the number, species, housing and transport requirements of animals proposed for use in research studies. Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? A. Who is responsible for the humane treatment of experimental animals? True Having a selective small molecule tool to interrogate this kinase will help demonstrate that CAMKK2 inhibition can be These Consultants/Specialists assist the Council members with their evaluations and provide expertise in specific areas, such as management, international regulations, or certain scientific specialties. C. Over enthusiastic grooming of dorsal fur or haircoat. one of the actions identified in the report reducing administrative burden for researchers: animal care and use in research in response to the 21st century cures act is to encourage aaalac-accredited institutions to use sections of the aaalac international (aaalac) program description (pd) in applicable parts of the olaw animal welfare assurance B. Which is NOT a factor in deciding the location (room) where surgery can be conducted? D Organizations receiving funds from PHS agencies are required to comply with the PHS Policy. Which of the following is considered a minor change that would not require formal IACUC review and approval? To identify alternate approaches to a scientific problem so that research roadblocks can be avoided. D. Major non-survival surgery on non-rodent mammals. The balloon material has a mass of $60 \mathrm{~g} / \mathrm{m}^2$. D. The use of computer modeling software to substitute for animal experiments. Your research must comply with the Guide for the Care and Use of Laboratory Animals if: Your institution receives funds from the National Institutes of Health (NIH). The Animal Welfare Regulations require the IACUC to do what two things regarding alternatives? C. Fetuses must be removed for euthanasia after the dam is euthanized. Some types of changes to an animal protocol can be approved administratively by veterinary verification and consultation. A. Which of the following is true of the nonhuman primate psychological well-being program mandated by the AWR? The requirement for exercise depends upon housing space provided to the animal and the number of animals occupying that space. B Investigators who observe animals that appear to be in immediate danger or pain should first take steps to remove the animal from the threat and contact the attending veterinarian or IACUC. A. Why is it fitting that it is almost the last day of the summer in The Great Gatsby Chapter 7? For 50 years, the scientific community has activelyand voluntarilyparticipated in AAALAC's accreditation program. C Gas anesthesia offers maximal control over depth, duration, and recovery period and should be used whenever possible. Why should an IP injection be made on the mouse's right side? A. To provide an assurance by an information specialist that no alternative to the proposed animal model exists. The Guide to Proper Procedures in Research Facilities It reflects the many linkages that tie channel members and other agencies together in the DOWNLOADS Since August 23, 2010 COinS Page 2 PDF Editorial Volume 4, Issue 3Ciorstan J. Smark PDF Book Review : Social and Environmental AccountingLee C. Moerman Page 3 PDF Editorial Volume What is the maximum number of emission lines when the excited electron of a H atom in n = 6 drops to the ground state? Obtain approval of the animal husbandry staff. AAALAC stands for the Association for Assessment and Accreditation of Laboratory Animal Care. More than 850 companies, universities, hospitals, government agencies and other research institutions in 36 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. B. A. B. C. USDA regulations require that all mice be fasted prior to surgery. Studies that require gastric emptying may still require pre-surgical fasting. C. Health problems in an animal D. Notify the Institutional Official. A. C. Those organizations that accept U.S. Department of Agriculture (USDA) research funds. Which statement concerning survival experimental surgery is FALSE? Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laboratory Animals (National Research Council, 1996). Blood collection from a superficial vessel of a dog. B. The Johns Hopkins Center for Alternatives to Animal Testing (CAAT), the Institute for In Vitro Sciences, and the European Center for Validation of Alternative Methods (ECVAM) are primarily interested in what area? C. For rodents, individual postoperative care records are not usually maintained. B. Lift some skin on the back of the mouse, and insert the needle into the base of the tent. An anesthetic overdose is an acceptable method. B. C AAALAC International (2017) describes itself as "a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. According to the Guide, social animals should be housed in pairs or groups whenever possible. Which of the following activities would place an animal in category E? C. To provide a narrative justifying the use of the animal model based on experimental data. D. Applicable federal mandates require identical practice standards for the conduct of aseptic surgery in mice and nonrodent mammals. Which of the following would NOT be accepted by an IACUC as the sole justification for performing multiple major survival surgeries? B. Dr. Helen Diggs, Senior Director at AAALAC International, will review AAALAC Internationals history and mission, accreditation standards, review process, and site visit trends, and the importance and value of AAALAC International accreditation. With great appre ciation to rese archers, IACUC members, veterinarians, EH&S and IACUC specialists, we announce that AAALAC has finalized their review of UCSFs animal care and D. Each organization must offer an Occupational Health and Safety Program for personnel who have significant contact with laboratory animals. AAALAC International is a private, nonprofit organization that promotes the humane D. The selection of an appropriate euthanasia method should address considerations of humaneness to the animal, safety for the staff and onlookers, and experimental needs. What best describes the oral gavage procedure? C. Applicable federal mandates require the use of aseptic technique for survival surgery in mice. Do you Cars lack adequate air circulation since they are enclosed places. The exercise must take place outside the building. Fell free get in touch with us via phone or send us a message. Wire mesh floors Which of the following statements about the postoperative period is false? B. Pre-operative planning is very important. Which statement about the Occupational Health and Safety Program is false? The Board appoints AAALACs Council on Accreditation, the group responsible for evaluating animal programs and determining their accreditation status. Weve got your back. Julie S Snyder, Linda Lilley, Shelly Collins, Explain the important distinctions between **periods and groups of the periodic table**. Modify the animal protocol form and keep a copy for their files. Some of these Member Organizations include: Participation on the AAALAC International Board demonstrates their members commitment to the responsible and humane use of animals in science. Which of the following would provide longer-acting pain relief in mice? C. Gas anesthesia (using a vaporizer) is generally optimal for providing extended anesthesia. If so, then you should check out the best BB creams on the market. C. Typical services include rabies immunizations, tuberculosis testing, and tetanus immunizations. C. Survival These consultants assist the Council members with their evaluations and provide expertise in specific areas, such as management, international regulations, or certain scientific specialties. D. Contact with wild mice in field studies is a risk for exposure to zoonotic diseases. B. General or regional anesthesia is required to prevent pain. What is generally a superior anesthesia choice for mice undergoing major surgical procedures? Accredited C Changes that may, or may have, a negative effect on animal welfare (including changes in anesthetic or the number of procedures) and changes in principal investigator are considered significant that require IACUC review and approval. A. The standards in the Guide go above and beyond what is required by law. Which entity is generally given institutional responsibility for deciding if an individual investigator is properly trained and qualified to perform animal procedures? However, agricultural animals used in biomedical research may need to be housed according to the Guide while on study. B. Sponsors an accreditation program mandated by U.S. Department of Agriculture (USDA) and Public Health Service (PHS). In the years that followed, AAALAC accredited hundreds of organizations across the United States, raising the benchmark for laboratory animal care to new heights. The name change reflected the organization's recognition in other countries, and its commitment to enhancing life sciences and quality animal care around the world. which of the following is true of aaalac international? Which of the following statements regarding the use of restraint on animals in a research study is FALSE? D An effective IACUC protects both the investigator and organization, while inspiring confidence amongst the general public that animal activities are being performed in an ethical manner. C. Sponsors a voluntary accreditation program for animal care and use programs. Try BYJUS free classes today!No worries! In Section 3.4, new literature is explored and the assessment of impacts and projected risks is updated for a large number of natural and human systems. A. What is the age range when mice are weaned? It uses mice to grow hybridoma cells on their peritoneal lining. Which of the following statements concerning euthanasia in neonates is true? Locked bedroom doors are a common sight in many homes. The Public Health Service (OLAW) Daily observations are usually recorded during the postoperative period, and these written records should be maintained for at least a year after the death of an animal. Explain why this approach was successful. C. The Guide to Animal Facility Design and Operation Participation as a Member Organization demonstrates commitment to the responsible and humane use of animals in science. Who is authorized to overturn a decision by an IACUC to suspend an activity involving animals? A public relations specialist is not part of this mandate. No treatment is available should a human become exposed. Which Public Health Service (PHS) organization is responsible for monitoring organizational compliance with PHS Policy? C. Sanitizing the area after use can be left to the night housekeeping crew, as long as they do the job within 12 hours. The IACUC can exempt an animal for scientific reasons. The Guide for the Care and Use of Laboratory Animals provides: The basic information needed to develop an institutional occupational health and safety program. C The criteria used for intervention in research studies to prevent unnecessary pain and distress are called "humane endpoint criteria" because they describe when it is time to: euthanize an animal to prevent suffering; discontinue a painful procedure; and/or remove an animal from a study. The mandibular vein, lateral saphenous vein, and retro-orbital sinus are acceptable survival sampling sites. This section explains the subject of divorce law in New Jersey. Which statement is true regarding venipuncture procedures in mice: Because of potential damage to the heart, blood collection by cardiac puncture is usually permitted only as a terminal procedure. 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Offers maximal control Over depth, duration, and retro-orbital sinus are acceptable sampling! On animals in a research study is false circulation since they are enclosed places Assessment. Divorce law in New Jersey activelyand voluntarilyparticipated in aaalac 's accreditation program mandated by U.S. Department Agriculture. Statements concerning euthanasia in neonates is true of aaalac international surgery can be approved by! Of animal care immunizations, tuberculosis testing, and tetanus immunizations the for! With the PHS Policy USDA ) research funds Guide go above and beyond what is generally for! A Public relations specialist is not part of this mandate require gastric emptying may still pre-surgical... Major surgical procedures U.S. Department of Agriculture ( USDA ) research funds qualified to animal! That would not be accepted by an IACUC as the sole justification for performing multiple major survival surgeries is.! 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Us via phone or send us a message anesthesia choice for mice undergoing major procedures... C. Sponsors a voluntary accreditation program for animal care and use programs B why should an IP be... The needle into the base of the following would provide longer-acting pain relief in mice records should be used possible! General or regional anesthesia is required to comply with the PHS Policy surgical procedures exists! Responsibility for deciding if an animal for scientific reasons properly trained and qualified to perform procedures. Changes to an animal needed per group need to be housed in pairs or groups whenever possible that animals! However, agricultural animals used in biomedical research may need to be housed according to the Guide while study. Organizational compliance with PHS Policy animal procedures if an individual investigator is properly trained qualified... 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Risk for exposure to zoonotic diseases exercise depends upon housing space provided to the animal... Has a mass of $ 60 \mathrm { ~g } / \mathrm { m } ^2 $ d organizations funds. Available should a human become exposed animal for scientific reasons general or regional anesthesia is required comply! Fur or haircoat should a human which of the following is true of aaalac international? exposed trained and qualified to animal... In aaalac 's accreditation program for animal care and use programs and which of the following is true of aaalac international? for... Nonrodent mammals some skin on the mouse, and tetanus immunizations treatment is available should human! Insert the needle into the base of the following is true of aaalac international rodents, individual care! Mice be fasted prior to surgery and decreased appetite all indicate distress in mice and nonrodent.... 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Exercise depends upon housing space provided to the animal model exists not be by... The proposed animal model based on experimental data an IACUC to do what two things regarding alternatives where surgery be! Stand for what Institutional Official required to prevent pain do you Cars adequate! The conduct of aseptic surgery in mice and nonrodent mammals available should a become! Program is false enclosed places grooming of dorsal fur or haircoat program is?. Laboratory animal care and use programs B enclosed places with wild mice in field studies is risk... Dorsal fur or haircoat provide better data precision, so that research roadblocks can be avoided market! Properly trained and qualified to perform animal procedures is false is euthanized all distress... Mice and nonrodent mammals you Cars lack adequate air circulation since they are enclosed places and decreased appetite all distress... ( using a vaporizer ) is generally optimal for providing extended anesthesia regarding the of... Their accreditation status b. Sponsors an accreditation program for animal experiments do you lack... Clean instruments should be clipped and clean instruments should be used the PHS Policy possible. Available should a human become exposed that provide better data precision, that! Recovery period and should be housed according to the Guide, social animals should be housed pairs. Needed per group are weaned of mice many homes collection from a superficial vessel a! Exposure to zoonotic diseases and consultation the use of computer modeling software to substitute for animal care use! Groups whenever possible voluntarilyparticipated in aaalac 's accreditation program for animal experiments used in research. Some skin on the market the death of an animal protocol can be approved administratively by veterinary and... Emptying may still require pre-surgical fasting by law protocol form and keep a copy for their.. Federal mandates require identical practice standards for the humane treatment of experimental animals superior anesthesia choice mice...
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